Echo-Planar Susceptibility Mapping
نویسندگان
چکیده
Purpose: Quantitative susceptibility mapping (QSM) is a valuable new approach for subcortical brain iron mapping [1,2]. However, acquisition times are typically on the order of 5-10 minutes, which is acceptable in dedicated studies but limits wider use in the clinic for standard brain exams due to the considerable time penalty. The aim is to develop and test an extremely rapid means (under 10 seconds) of acquiring whole brain QSM to study subcortical brain iron.
منابع مشابه
Single-shot T(2)* mapping with 3D compensation of local susceptibility gradients in multiple regions.
Macroscopic magnetic field inhomogeneities severely limit sensitivity of blood oxygenation level-dependent (BOLD) functional MRI (fMRI) in frontal and central brain regions close to brain stem. A single-shot multiecho echo-planar imaging method (TurboPEPSI) was developed that combines quantitative T(2)* mapping with gradient compensation of local susceptibility inhomogeneities in multiple volum...
متن کاملRapid isotropic diffusion mapping without susceptibility artifacts: whole brain studies using diffusion-weighted single-shot STEAM MR imaging.
A subsecond magnetic resonance imaging (MRI) technique for isotropic diffusion mapping is described which, in contrast to echo-planar imaging (EPI), is insensitive to resonance offsets, i.e., tissue susceptibility differences, magnetic field inhomogeneities, and chemical shifts. It combines a diffusion-weighted (DW) spin-echo preparation period and a high-speed stimulated echo acquisition mode ...
متن کاملRapid multi-orientation quantitative susceptibility mapping
Three-dimensional gradient echo (GRE) is the main workhorse sequence used for susceptibility weighted imaging (SWI), quantitative susceptibility mapping (QSM), and susceptibility tensor imaging (STI). Achieving optimal phase signal-to-noise ratio requires late echo times, thus necessitating a long repetition time (TR). Combined with the large encoding burden of whole-brain coverage with high re...
متن کاملSingle-step quantitative susceptibility mapping with variational penalties.
Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from the gradient echo (GRE) phase signal through background phase removal and dipole inversion steps. Each of these steps typically requires the solution of an ill-posed inverse problem and thus necessitates additional regularization. Recently developed single-step QSM algorithms directly relate t...
متن کاملReduced susceptibility effects in perfusion fMRI with single-shot spin-echo EPI acquisitions at 1.5 Tesla.
Arterial spin labeling (ASL) perfusion contrast is not based on susceptibility effects and can therefore be used to study brain function in regions of high static inhomogeneity. As a proof of concept, single-shot spin-echo echo-planar imaging (EPI) acquisition was carried out with a multislice continuous ASL (CASL) method at 1.5T. A bilateral finger tapping paradigm was used in the presence of ...
متن کامل